New treatments for dementia
and Alzheimer's disease

 

 

Method of Doctor Statnikov. Alzheimer's disease

Agenzia di reclutamento «Smart Hunter»

Alzheimer's disease –
problems of diagnosis and treatment prospects

Alzheimer's disease - a neurodegenerative disease that can develop decades and is characterized by loss of memory, changes in behavior, motor function failure. Cognitive disorders that accompany the development of Alzheimer's disease, converted the last few years, and sometimes decades, people's lives and their loved ones in hell. WHO predicts that the disease could be one of the worst pathologies of the XXI century and the annual damage caused by it the world economy can grow in the coming decades to a few trillion dollars. It should recognize the tragic fact that currently there are only scientific hypotheses, scientific and technical projects and hopes, but effective drugs for Alzheimer's disease is not present. As in this situation to treat and support people suffering from Alzheimer's disease?

On the causes of Alzheimer's disease, there are many opinions. The most common by far is the theory of the formation of beta-amyloid plaques. This occurs through the formation of beta-amyloid bonding in a so-called beta-layers. Layers grow and form insoluble plaques. Scientists believe that these plaques and lead to the destruction of neurons in the brain and progressive degradation. However, there is evidence indicating that the presence of amyloid plaques do not necessarily lead to the development of Alzheimer's disease. By competing version not destroy healthy cells plaques and beta amyloid itself. "These proteins are constantly present in the human body. There is speculation that they are part of the brain's immune system, and can be released in response to a hit in the brain viruses and bacteria on inflammatory injury mikrosotryaseniya which are, for example, in sports. "When the immune cells in the body becomes too much, they do not begin to attack bacteria and viruses, and healthy cells, in this case - the neurons, but as they say among the people, horseradish radish is not sweeter!

It is not known exactly how amyloid proteins kill brain. Although their participation is almost universally recognized to date, it does not help in the development of practical treatment of Alzheimer's disease. The lights of hope from time to time pro-lit press and media, but quickly fade in today's tragic reality.

Diagnosis of Alzheimer's disease

Now a little about the diagnosis. Usually, the first explores memory deficits. And, do not take the normal forgetfulness, which we sometimes complain of the fact of the presence of dementia. We are talking about very specific violations. Alzheimer's disease leads to defeat certain brain regions, most notably, those that are responsible for episodic memory. If there is serious suspicion of Alzheimer's disease, the diagnosis should be confirmed by other research methods:. MRI study of cerebrospinal fluid for the presence of amyloid protein, neuropsychological thinking tests, behavior and orientation, and others in the scientific press and the media present information that the early diagnosis of the disease Alzheimer possible. For example, according to the technology developers and Diamentech Neurotrack possible to answer the question, what parts of the brain affected in the early stages of the disease and test them directed state even at a time when the loss of cognitive functions is almost imperceptible. The expediency of having such opportunities for the practice of medicine is undeniable. But where are they? And if they are already in principle, it will be available when a diagnostic for Alzheimer's patients around the world? And before the medical task: to diagnose and treat today, and diagnose and treat today, better and more successful than the last!

However, in daily practice, even with MRI and other modern methods of diagnostics enough, Alzheimer's disease is usually diagnosed too late, already at the stage of overt dementia when behavioral symptoms speak for themselves. The danger of this disease for mankind is underestimated and remains in the shadow of such terrible pathologies such as cancer. However, the problem of late diagnosis of Alzheimer's disease is similar to the similar problem of cancer but, unlike cancer, initial symptoms of which virtually no definable or methods laboratory and functional diagnosis, nor, moreover, by simple observation, early signs of dementia, and in particular, diseases Alzheimer's, are well known and are not only visible inner circle, but also to the patient. This makes it possible to talk about the possibility of early prevention of these diseases. Even if the diagnosis has not yet been delivered, and MRI does not reveal obvious problems, but the person concerned about such manifestations as impaired memory, thinking, orientation in a familiar space, difficulty understanding speech, and so on., There is a sense, not waiting for the progression of these symptoms to the stage apparent violations, take measures to prevent the development of pathological symptoms. In particular, it is possible to undergo therapy in activation group homeostasis.

Used in such therapy undifferentiated preventive effect based on the principle of activating the body as self-regulating system for maintaining homeostasis. At a time when people, as the system is in a harmonious and balanced state, each element of this system also tends to come in a harmonious state, which greatly complicates the possibility of the existence and development of various pathological processes and formations.

And it is possible to do today!

Is there an answer to the question "how to treat Alzheimer's disease"?

Remarkable view of the domestic scientist-neurologist Zakharov, professor of the Department of Nervous Diseases and Neurosurgery of the First Moscow State Medical University named after Sechenov, that the lion's share of start-ups, the goal of which implies a certain knowledge of how to treat Alzheimer's disease, is a common characteristic feature - very vague explanation of the principle of the work promoted by the technology. At the same time, developments were not disclosed details of the alleged purpose of protecting intellectual property. However, it does not stop investors. For example, over the past two years the company has managed to attract Halo Neuroscience and a half, and the company YBrain more than $ 4 million investment.

But despite the impressive amount of investment actually operating methods and products in the market has not appeared. Doctors today still nothing to treat their patients! Evidence-based and practice-tested approach to the treatment of patients with Alzheimer's disease is not present, as well as missing and remedies. "Today, there are several medications that reduce symptoms, improve memory, but does not affect the progression of the disease, that is carried out only symptomatic treatment. But the pathogenic agent that could stop the progression of the disease, has not yet been developed. Scientists are still trying to find an answer to the question "how to treat Alzheimer's disease?", Developing new medicines and looking for other ways to stop the degradation of the brain.

Alzheimer's problem - what to do?

In socio-economic terms, disorders caused by Alzheimer's disease, creating a huge amount of everyday problems and the very sick, and those who care for them. Older people gradually forget what to do in the most ordinary and familiar situations and lose the ability to adequate independence, which often leads to very negative consequences. For example, many elderly people are suffering from financial fraud: they participate in the sweepstakes, make contributions to obscure their organizations and foundations become "magical" medical devices and drugs. To protect elderly people from such situations in general, and especially of Alzheimer's patients, keeping them very problematic equality in public life. Relatives and friends of the patient have to fully or partially abandon their professional activity, which generally deteriorating economic and perhaps social situation in the family. This situation also makes a negative contribution to the general public and economic damage.

We should not lose sight of the fact that not all of these patients have relatives that can fully take care of them. Many people will sooner or later end up in nursing homes or specialized clinics. In contradiction to the principles of the treatment and care of these patients developed an English psychologist Tom Kitvudom, even in the best private schools people are almost completely deprived of independence, are trapped in the hospital walls. They are mostly for calm staff forced to take potent sedatives. They are as people, survivors of the mind, which left only wait for death.

What to do with this very not simple problem? To ensure that the situation has changed with Alzheimer's disease, I have to change the approach to the solution of this problem at the state level. Otherwise, due to Alzheimer's disease we are waiting for a very tragic consequences, as in the opinion of credible experts, for example, Vladimir Zakharov, Alzheimer's disease - the future of every three of us!

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